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Expression of a dominant negative TrkB receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal neurons

We have developed a method to analyze the relative contributions of pre- and postsynaptic actions of a particular gene product in neurons in culture and potentially in slices using adenovirus-mediated gene transfer. A recombinant virus directed the expression of both a GFP reporter protein and TrkB....

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Detalhes bibliográficos
Main Authors: Li, Yong-Xin, Xu, Youfeng, Ju, Donghong, Lester, Henry A., Davidson, Norman, Schuman, Erin M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27990/
https://ncbi.nlm.nih.gov/pubmed/9724799
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