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Synthesis of the Cores of Hypocrellin and Shiraiachrome: Diastereoselective 1,8-Diketone Aldol Cyclization

[Image: see text] Intramolecular 1,8-diketone aldol reactions were studied as a tool for the construction of the 7-membered rings of hypocrellin and shiraiachrome. Conditions were identified to obtain the relative stereochemistries present in the two natural products with excellent diastereoselectiv...

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Autori principali: O’Brien, Erin M., Li, Jingxian, Carroll, Patrick J., Kozlowski, Marisa C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798919/
https://ncbi.nlm.nih.gov/pubmed/19894740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo9018914
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