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An Efficient Synthesis of (±)-Grandisol Featuring 1,5-Enyne Metathesis

[Image: see text] An eight step synthesis of (±)-grandisol features a key sequence involving a high-yielding, microwave-assisted enyne metathesis to yield a 1-alkenylcyclobutene that is semihydrogenated to yield a silyl-protected grandisol. Metathesis catalyst screens revealed an intriguing trend wh...

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Bibliografiset tiedot
Päätekijät: Graham, Thomas J. A., Gray, Erin E., Burgess, James M., Goess, Brian C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798917/
https://ncbi.nlm.nih.gov/pubmed/19957923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo9020375
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