Visualizing the von Willebrand factor/glycoprotein Ib-IX axis with a platelet-type von Willebrand disease mutation

Platelet-type von Willebrand disease (PT-VWD) is a bleeding disorder of the platelet glycoprotein Ib-IX/von Willebrand factor (VWF) axis caused by mutations in the glycoprotein Ib-IX receptor that lead to an increased affinity with VWF. In this report, platelets from a mouse expressing a mutation as...

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Autors principals: Guerrero, Jose A., Kyei, Mark, Russell, Susan, Liu, Junling, Gartner, T. Kent, Storrie, Brian, Ware, Jerry
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
Matèries:
Thrombosis and Hemostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798865/
https://ncbi.nlm.nih.gov/pubmed/19808696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-210823
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