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Detection of nonneutral substitution rates on mammalian phylogenies

Methods for detecting nucleotide substitution rates that are faster or slower than expected under neutral drift are widely used to identify candidate functional elements in genomic sequences. However, most existing methods consider either reductions (conservation) or increases (acceleration) in rate...

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Detalhes bibliográficos
Main Authors: Pollard, Katherine S., Hubisz, Melissa J., Rosenbloom, Kate R., Siepel, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798823/
https://ncbi.nlm.nih.gov/pubmed/19858363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.097857.109
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