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Estimating population genetic parameters and comparing model goodness-of-fit using DNA sequences with error

It is known that sequencing error can bias estimation of evolutionary or population genetic parameters. This problem is more prominent in deep resequencing studies because of their large sample size n, and a higher probability of error at each nucleotide site. We propose a new method based on the co...

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Detalhes bibliográficos
Main Authors: Liu, Xiaoming, Fu, Yun-Xin, Maxwell, Taylor J., Boerwinkle, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798822/
https://ncbi.nlm.nih.gov/pubmed/19952140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.097543.109
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