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Inferring Population Mutation Rate and Sequencing Error Rate Using the SNP Frequency Spectrum in a Sample of DNA Sequences
One challenge of analyzing samples of DNA sequences is to account for the nonnegligible polymorphisms produced by error when the sequencing error rate is high or the sample size is large. Specifically, those artificial sequence variations will bias the observed single nucleotide polymorphism (SNP) f...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2734145/ https://ncbi.nlm.nih.gov/pubmed/19318520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msp059 |
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