Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists

A series of non-vanillyl resiniferatoxin analogues, having 4-methylsulfonylaminophenyl and fluorophenyl moieties as vanillyl surrogates, have been investigated as ligands for rat TRPV1 heterologously expressed in Chinese hamster ovary cells. Although lacking the metabolically problematic 4-hydroxy s...

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Detalhes bibliográficos
Main Authors: Choi, Hyun-Kyung, Choi, Sun, Lee, Yoonji, Kang, Dong Wook, Ryu, HyungChul, Maeng, Han-Joo, Chung, Suk-Jae, Pavlyukovets, Vladimir A., Pearce, Larry V., Toth, Attila, Tran, Richard, Wang, Yun, Morgan, Matthew A., Blumberg, Peter M., Lee, Jeewoo
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798733/
https://ncbi.nlm.nih.gov/pubmed/19135377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.11.085
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