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Conformationally Constrained Analogues of N'-(4-t-Butylbenzyl)-N-(4-Methylsulfonylaminobenzyl)Thiourea as TRPV1 Antagonists

A series of bicyclic analogues having indan and tetrahydronaphthalene templates in the A-region were designed as conformationally constrained analogues of our previously reported potent TRPV1 antagonists (1, 3). The activities for rat TRPV1 of the conformationally restricted analogues were moderatel...

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Detaylı Bibliyografya
Asıl Yazarlar:	Ryu, HyungChul, Lim, Ju-Ok, Kang, Dong Wook, Pearce, Larry V., Tran, Richard, Toth, Attila, Lee, Jeewoo, Blumberg, Peter M.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	2008
Konular:	Article
Online Erişim:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3420357/ https://ncbi.nlm.nih.gov/pubmed/18406014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2008.02.026
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Conformationally Constrained Analogues of N'-(4-t-Butylbenzyl)-N-(4-Methylsulfonylaminobenzyl)Thiourea as TRPV1 Antagonists

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