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New roles for Notch in tuberous sclerosis

Tuberous sclerosis complex (TSC) is a dominantly inherited disease that is characterized by the growth of multiple benign tumors that are often difficult to treat. TSC is caused by mutations that inactivate the TSC1 or TSC2 genes, which normally function to inhibit activation of mammalian target of...

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Dettagli Bibliografici
Autore principale: Pear, Warren S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798710/
https://ncbi.nlm.nih.gov/pubmed/20038806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41897
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