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New roles for Notch in tuberous sclerosis
Tuberous sclerosis complex (TSC) is a dominantly inherited disease that is characterized by the growth of multiple benign tumors that are often difficult to treat. TSC is caused by mutations that inactivate the TSC1 or TSC2 genes, which normally function to inhibit activation of mammalian target of...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798710/ https://ncbi.nlm.nih.gov/pubmed/20038806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41897 |
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