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Tuberous sclerosis complex: everything old is new again

Tuberous Sclerosis Complex (TSC) is a multiorgan genetic disease caused by loss of function of either the TSC1 (encodes hamartin) or TSC2 (encodes tuberin) genes. Patients with TSC have benign tumors (hamartomas) in multiple organs though brain involvement is typically the most disabling aspect of t...

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Bibliographic Details
Main Author: Ess, Kevin C.
Format: Artigo
Language:Inglês
Published: Springer US 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164024/
https://ncbi.nlm.nih.gov/pubmed/21547713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11689-009-9014-y
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