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The Rho/Rac exchange factor Vav2 controls nitric oxide–dependent responses in mouse vascular smooth muscle cells

The regulation of arterial contractility is essential for blood pressure control. The GTPase RhoA promotes vasoconstriction by modulating the cytoskeleton of vascular smooth muscle cells. Whether other Rho/Rac pathways contribute to blood pressure regulation remains unknown. By studying a hypertensi...

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Détails bibliographiques
Auteurs principaux: Sauzeau, Vincent, Sevilla, María A., Montero, María J., Bustelo, Xosé R.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798677/
https://ncbi.nlm.nih.gov/pubmed/20038798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38356
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