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The Rho/Rac exchange factor Vav2 controls nitric oxide–dependent responses in mouse vascular smooth muscle cells

The regulation of arterial contractility is essential for blood pressure control. The GTPase RhoA promotes vasoconstriction by modulating the cytoskeleton of vascular smooth muscle cells. Whether other Rho/Rac pathways contribute to blood pressure regulation remains unknown. By studying a hypertensi...

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Autori principali: Sauzeau, Vincent, Sevilla, María A., Montero, María J., Bustelo, Xosé R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798677/
https://ncbi.nlm.nih.gov/pubmed/20038798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38356
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