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Enhanced Selection of High Affinity DNA-Reactive B Cells Following Cyclophosphamide Treatment in Mice

A major goal for the treatment of patients with systemic lupus erythematosus with cytotoxic therapies is the induction of long-term remission. There is, however, a paucity of information concerning the effects of these therapies on the reconstituting B cell repertoire. Since there is recent evidence...

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Detalhes bibliográficos
Main Authors: Kawabata, Daisuke, Venkatesh, Jeganathan, Ramanujam, Meera, Davidson, Anne, Grimaldi, Christine M., Diamond, Betty
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798615/
https://ncbi.nlm.nih.gov/pubmed/20066044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008418
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