Antigen Is Required for Maturation and Activation of Pathogenic Anti-DNA Antibodies and Systemic Inflammation

Systemic lupus erythematosus is an autoimmune disease characterized by autoantibodies and systemic inflammation that results in part from dendritic cell activation by nucleic acid containing immune complexes. There are many mouse models of lupus, some spontaneous and some induced. We have been inter...

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Main Authors: Venkatesh, Jeganathan, Yoshifuji, Hajime, Kawabata, Daisuke, Chinnasamy, Prameladevi, Stanevsky, Anfisa, Grimaldi, Christine M., Cohen-Solal, Joel, Diamond, Betty
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192436/
https://ncbi.nlm.nih.gov/pubmed/21444762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000224
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