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Hepatitis C Virus-Linked Mitochondrial Dysfunction Promotes Hypoxia-Inducible Factor 1α-Mediated Glycolytic Adaptation
Hepatitis C virus (HCV) infection induces a state of oxidative stress by affecting mitochondrial-respiratory-chain activity. By using cell lines inducibly expressing different HCV constructs, we showed previously that viral-protein expression leads to severe impairment of mitochondrial oxidative pho...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
American Society for Microbiology (ASM)
2010
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798449/ https://ncbi.nlm.nih.gov/pubmed/19846525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00769-09 |
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