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Targeting Endoplasmic Reticulum and/or Mitochondrial Ca(2+) Fluxes as Therapeutic Strategy for HCV Infection

Chronic hepatitis C is characterized by metabolic disorders and by a microenvironment in the liver dominated by oxidative stress, inflammation and regeneration processes that can in the long term lead to liver cirrhosis and hepatocellular carcinoma. Several lines of evidence suggest that mitochondri...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Scrima, Rosella, Piccoli, Claudia, Moradpour, Darius, Capitanio, Nazzareno
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871704/
https://ncbi.nlm.nih.gov/pubmed/29619366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00073
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