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Mechanisms of Protein Kinase PKR-Mediated Amplification of Beta Interferon Induction by C Protein-Deficient Measles Virus

The measles virus P gene products V and C antagonize the host interferon (IFN) response, blocking both IFN signaling and production. Using Moraten vaccine strain-derived measles virus and isogenic mutants deficient for either V or C protein production (V(ko) and C(ko), respectively), we observed tha...

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Autors principals: McAllister, Christopher S., Toth, Ann M., Zhang, Ping, Devaux, Patricia, Cattaneo, Roberto, Samuel, Charles E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798421/
https://ncbi.nlm.nih.gov/pubmed/19846517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02630-08
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