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Protein Kinase PKR Catalytic Activity is Required for the PKR-dependent Activation of Mitogen-activated Protein Kinases and Amplification of Interferon Beta Induction following Virus Infection
The protein kinase regulated by RNA (PKR) enhances both activation of mitogen-activated protein kinases and the induction of interferon beta (IFN-β) by measles virus defective in C protein expression (C(ko)). Here we used complementation of human cell lines stably deficient in PKR (PKR(kd)) to probe...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3313008/ https://ncbi.nlm.nih.gov/pubmed/22381929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.01.029 |
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