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Modulation of Hepatitis C Virus RNA Abundance and the Isoprenoid Biosynthesis Pathway by MicroRNA miR-122 Involves Distinct Mechanisms

MicroRNA 122 (miR-122) promotes hepatitis C virus (HCV) RNA abundance through a direct interaction with the viral RNA and stimulates the mevalonate pathway in the animal liver. We found that overexpression of miR-122 enhanced viral RNA accumulation without affecting genes in the mevalonate pathway,...

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Sonraí Bibleagrafaíochta
Main Authors: Norman, Kara L., Sarnow, Peter
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798415/
https://ncbi.nlm.nih.gov/pubmed/19846523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01156-09
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