Murine Hepatitis Virus Nonstructural Protein 4 Regulates Virus-Induced Membrane Modifications and Replication Complex Function

Positive-strand RNA viruses induce modifications of cytoplasmic membranes to form replication complexes. For coronaviruses, replicase nonstructural protein 4 (nsp4) has been proposed to function in the formation and organization of replication complexes. Murine hepatitis virus (MHV) nsp4 is glycosyl...

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Detalhes bibliográficos
Main Authors: Gadlage, Mark J., Sparks, Jennifer S., Beachboard, Dia C., Cox, Reagan G., Doyle, Joshua D., Stobart, Christopher C., Denison, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798404/
https://ncbi.nlm.nih.gov/pubmed/19846526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01772-09
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