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Mutations in the Ectodomain of Newcastle Disease Virus Fusion Protein Confer a Hemagglutinin-Neuraminidase-Independent Phenotype

The entry of enveloped viruses into host cells is preceded by membrane fusion, which in paramyxoviruses is triggered by the fusion (F) protein. Refolding of the F protein from a metastable conformation to a highly stable postfusion form is critical for the promotion of fusion, although the mechanism...

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Detalhes bibliográficos
Main Authors: Ayllón, Juan, Villar, Enrique, Muñoz-Barroso, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798362/
https://ncbi.nlm.nih.gov/pubmed/19906934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01473-09
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