Fusion Deficiency Induced by Mutations at the Dimer Interface in the Newcastle Disease Virus Hemagglutinin-Neuraminidase Is due to a Temperature-Dependent Defect in Receptor Binding

The tetrameric paramyxovirus hemagglutinin-neuraminidase (HN) protein mediates attachment to sialic acid-containing receptors as well as cleavage of the same moiety via its neuraminidase (NA) activity. The X-ray crystallographic structure of an HN dimer from Newcastle disease virus (NDV) suggests th...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Corey, Elizabeth A., Mirza, Anne M., Levandowsky, Elizabeth, Iorio, Ronald M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12768010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.12.6913-6922.2003
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