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Site-Specific Phosphorylation Induces Functionally Active Conformation in the Intrinsically Disordered N-Terminal Activation Function (AF1) Domain of the Glucocorticoid Receptor

Intrinsically disordered (ID) regions are disproportionately higher in cell signaling proteins and are predicted to have much larger frequency of phosphorylation sites than ordered regions, suggesting an important role in their regulatory capacity. In this study, we show that AF1, an ID activation d...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Garza, Anna M. S., Khan, Shagufta H., Kumar, Raj
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology (ASM) 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798295/
https://ncbi.nlm.nih.gov/pubmed/19841061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00552-09
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