Conditional Deletion of Neuronal Cyclin-Dependent Kinase 5 in Developing Forebrain Results in Microglial Activation and Neurodegeneration

Neuronal migration disorders are often identified in patients with epilepsy refractory to medical treatment. The prolonged or repeated seizures are known to cause neuronal death; however, the mechanism underlying seizure-induced neuronal death remains to be elucidated. An essential role of cyclin-de...

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Autores principales: Takahashi, Satoru, Ohshima, Toshio, Hirasawa, Motoyuki, Pareek, Tej K., Bugge, Thomas H., Morozov, Alexei, Fujieda, Kenji, Brady, Roscoe O., Kulkarni, Ashok B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2010
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797893/
https://ncbi.nlm.nih.gov/pubmed/19948833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.081158
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