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Aspartic acid-484 of nascent placental alkaline phosphatase condenses with a phosphatidylinositol glycan to become the carboxyl terminus of the mature enzyme.

A carboxyl-terminal chymotryptic peptide from mature human placental alkaline phosphatase was purified by HPLC and monitored by a specific RIA. Sequencing and amino acid assay showed that the carboxyl terminus of the peptide was aspartic acid, representing residue 484 of the proenzyme as deduced fro...

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Detalhes bibliográficos
Main Authors: Micanovic, R, Bailey, C A, Brink, L, Gerber, L, Pan, Y C, Hulmes, J D, Udenfriend, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC279778/
https://ncbi.nlm.nih.gov/pubmed/3422741
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