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Conversion of placental alkaline phosphatase from a phosphatidylinositol-glycan-anchored protein to an integral transmembrane protein.

Placental alkaline phosphatase (PLAP) is normally anchored to the plasma membrane of cells by a phosphatidylinositol-glycan anchor after removal of a carboxyl-terminal peptide from the nascent enzyme. To investigate the signals required for this processing we constructed a chimeric cDNA. The latter...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Berger, J, Micanovic, R, Greenspan, R J, Udenfriend, S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286715/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2646636/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.5.1457
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