Biosynthesis of phosphatidylinositol-glycan (PI-G)-anchored membrane proteins in cell-free systems: cleavage of the nascent protein and addition of the PI-G moiety depend on the size of the COOH-terminal signal peptide.

Nascent translation products of PI-G-anchored membrane proteins contain both NH2- and COOH-terminal signal sequences of approximately 15-30 residues that are removed during processing. Removal of the latter occurs concomitant with the addition of the PI-G moiety to the newly formed COOH terminus. In...

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Detalhes bibliográficos
Main Authors: Kodukula, K, Cines, D, Amthauer, R, Gerber, L, Udenfriend, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC48447/
https://ncbi.nlm.nih.gov/pubmed/1531539
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