KRAS Genotyping of Paraffin-Embedded Colorectal Cancer Tissue in Routine Diagnostics: Comparison of Methods and Impact of Histology

KRAS mutation testing before anti-epidermal growth factor receptor therapy of metastatic colorectal cancer has become mandatory in Europe. However, considerable uncertainty exists as to which methods for detection can be applied in a reproducible and economically sound manner in the routine diagnost...

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Main Authors: Weichert, Wilko, Schewe, Christiane, Lehmann, Annika, Sers, Christine, Denkert, Carsten, Budczies, Jan, Stenzinger, Albrecht, Joos, Hans, Landt, Olfert, Heiser, Volker, Röcken, Christoph, Dietel, Manfred
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2010
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797716/
https://ncbi.nlm.nih.gov/pubmed/20007841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2010.090079
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