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Origin of Irreversibility of Cell Cycle Start in Budding Yeast

Budding yeast cells irreversibly commit to a new division cycle at a regulatory transition called Start. This essential decision-making step involves the activation of the SBF/MBF transcription factors. SBF/MBF promote expression of the G1 cyclins encoded by CLN1 and CLN2. Cln1,2 can activate their...

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Autori principali: Charvin, Gilles, Oikonomou, Catherine, Siggia, Eric D., Cross, Frederick R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797597/
https://ncbi.nlm.nih.gov/pubmed/20087409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000284
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