Distribution, persistence and efficacy of adoptively transferred central and effector memory-derived autologous SIV-specific CD8(+) T-cell clones in rhesus macaques during acute infection

Plasma viremia decreases coincident with the appearance of virus-specific CD8(+) T cells during acute HIV or SIV infection. This finding, along with demonstrations of viral mutational escape from CD8(+) T-cell responses and transient increase in plasma viremia after depletion of CD8(+) T cells in SI...

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Hauptverfasser: Minang, Jacob T., Trivett, Matthew T., Bolton, Diane L., Trubey, Charles M., Estes, Jacob D., Li, Yuan, Smedley, Jeremy, Pung, Rhonda, Rosati, Margherita, Jalah, Rashmi, Pavlakis, George N., Felber, Barbara K., Piatak, Michael, Roederer, Mario, Lifson, Jeffrey D., Ott, David E., Ohlen, Claes
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797560/
https://ncbi.nlm.nih.gov/pubmed/19949091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902410
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