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Targeting PTPs with small molecule inhibitors in cancer treatment
Protein tyrosine phosphorylation plays a major role in cellular signaling. The level of tyrosine phosphorylation is controlled by protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs). Disturbance of the normal balance between PTK and PTP activity results in aberrant tyrosine phos...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797549/ https://ncbi.nlm.nih.gov/pubmed/18259840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-008-9113-3 |
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