Pumiliotoxin B binds to a site on the voltage-dependent sodium channel that is allosterically coupled to other binding sites.

Pumiliotoxin B (PTX-B), an alkaloid that has cardiotonic and myotonic activity, increases sodium influx in guinea pig cerebral cortical synaptoneurosomes. In the presence of scorpion venom (Leiurus) or purified alpha-scorpion toxin, the PTX-B-induced sodium influx is enhanced severalfold. PTX-B alon...

Descripció completa

Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Gusovsky, F, Rossignol, D P, McNeal, E T, Daly, J W
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1988
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2448797/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.4.1272
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!