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In situ hybridization of nucleus basalis neurons shows increased beta-amyloid mRNA in Alzheimer disease.
To determine which cells within the brain produce beta-amyloid mRNA and to assess expression of the beta-amyloid gene in Alzheimer disease, we analyzed brain tissue from Alzheimer and control patients by in situ hybridization. Our results demonstrate that beta-amyloid mRNA is produced by neurons in...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3277188/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.4.1227 |
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