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In situ hybridization of nucleus basalis neurons shows increased beta-amyloid mRNA in Alzheimer disease.

To determine which cells within the brain produce beta-amyloid mRNA and to assess expression of the beta-amyloid gene in Alzheimer disease, we analyzed brain tissue from Alzheimer and control patients by in situ hybridization. Our results demonstrate that beta-amyloid mRNA is produced by neurons in...

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Detalhes bibliográficos
Main Authors: Cohen, M L, Golde, T E, Usiak, M F, Younkin, L H, Younkin, S G
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC279740/
https://ncbi.nlm.nih.gov/pubmed/3277188
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