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Decreased choline acetyltransferase mRNA expression in the nucleus basalis of Meynert in Alzheimer disease: an in situ hybridization study.

The subnormal choline acetyltransferase (ChoAcTase) activity in the cerebral cortex of patients with Alzheimer disease (AD) is thought to originate from the loss of cholinergic neurons in the nucleus basalis of Meynert (nbM). To examine possible changes in the functional activity of the remaining ch...

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Detalhes bibliográficos
Main Authors: Strada, O, Vyas, S, Hirsch, E C, Ruberg, M, Brice, A, Agid, Y, Javoy-Agid, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50169/
https://ncbi.nlm.nih.gov/pubmed/1409664
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