Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immunodominant T-cell domains map to the polymorphic regions of the molecule.

The definition of human T-cell antigenic sites is important for subunit vaccine development of a peptide immunogen if the goal is to allow antibody boosting during infection or to stimulate antibody-independent T-cell immunity. To identify such sites on the circumsporozoite (CS) protein of Plasmodiu...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Good, M F, Pombo, D, Quakyi, I A, Riley, E M, Houghten, R A, Menon, A, Alling, D W, Berzofsky, J A, Miller, L H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1988
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Research Article
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279734/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2448793/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.4.1199
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