Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immunodominant T-cell domains map to the polymorphic regions of the molecule.

The definition of human T-cell antigenic sites is important for subunit vaccine development of a peptide immunogen if the goal is to allow antibody boosting during infection or to stimulate antibody-independent T-cell immunity. To identify such sites on the circumsporozoite (CS) protein of Plasmodiu...

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Detalhes bibliográficos
Main Authors: Good, M F, Pombo, D, Quakyi, I A, Riley, E M, Houghten, R A, Menon, A, Alling, D W, Berzofsky, J A, Miller, L H
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC279734/
https://ncbi.nlm.nih.gov/pubmed/2448793
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