Antigenic diversity in the circumsporozoite protein of Plasmodium falciparum abrogates cytotoxic-T-cell recognition.

Genetic analysis of field isolates of Plasmodium falciparum has shown selective accumulation of point mutations within the immunologically sensitive sites of the circumsporozoite (CS) protein, a vaccine candidate against malaria. This raised concern whether a vaccine containing the sequence of a sel...

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Bibliografiske detaljer
Main Authors: Udhayakumar, V, Shi, Y P, Kumar, S, Jue, D L, Wohlhueter, R M, Lal, A A
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC186295/
https://ncbi.nlm.nih.gov/pubmed/7510668
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