Antigenic diversity in the circumsporozoite protein of Plasmodium falciparum abrogates cytotoxic-T-cell recognition.

Genetic analysis of field isolates of Plasmodium falciparum has shown selective accumulation of point mutations within the immunologically sensitive sites of the circumsporozoite (CS) protein, a vaccine candidate against malaria. This raised concern whether a vaccine containing the sequence of a sel...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Udhayakumar, V, Shi, Y P, Kumar, S, Jue, D L, Wohlhueter, R M, Lal, A A
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1994
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC186295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7510668/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.4.1410-1413.1994
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