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Interferon-Inducible IFI16, a Negative Regulator of Cell Growth, Down-Regulates Expression of Human Telomerase Reverse Transcriptase (hTERT) Gene

BACKGROUND: Increased levels of interferon (IFN)-inducible IFI16 protein (encoded by the IFI16 gene located at 1q22) in human normal prostate epithelial cells and diploid fibroblasts (HDFs) are associated with the onset of cellular senescence. However, the molecular mechanisms by which the IFI16 pro...

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Autors principals: Song, Lynda Li, Ponomareva, Larissa, Shen, Hui, Duan, Xin, Alimirah, Fatouma, Choubey, Divaker
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797294/
https://ncbi.nlm.nih.gov/pubmed/20052289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008569
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