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The HECT Domain of the Ubiquitin Ligase Rsp5 Contributes to Substrate Recognition
Ubiquitin modification of endosomal membrane proteins is a signal for active inclusion into the Multivesicular Body (MVB) pathway, resulting in lysosomal degradation. However, the endosome represents a dynamic site of protein sorting with a majority of proteins destined for recycling, rather than MV...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797283/ https://ncbi.nlm.nih.gov/pubmed/19744925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.048629 |
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