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Tyrosine Phosphorylation of K(ir)3 following κ-Opioid Receptor Activation of p38 MAPK Causes Heterologous Desensitization
Prior studies showed that tyrosine 12 phosphorylation in the N-terminal, cytoplasmic domain of the G-protein-gated inwardly rectifying potassium channel, K(ir)3.1 facilitates channel deactivation by increasing intrinsic GTPase activity of the channel. Using a phosphoselective antibody directed again...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797258/ https://ncbi.nlm.nih.gov/pubmed/19773548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053793 |
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