Substrate Binding and Active Site Residues in RNases E and G: ROLE OF THE 5′-SENSOR

The paralogous endoribonucleases, RNase E and RNase G, play major roles in intracellular RNA metabolism in Escherichia coli and related organisms. To assay the relative importance of the principal RNA binding sites identified by crystallographic analysis, we introduced mutations into the 5′-sensor,...

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Detalhes bibliográficos
Main Authors: Garrey, Stephen M., Blech, Michaela, Riffell, Jenna L., Hankins, Janet S., Stickney, Leigh M., Diver, Melinda, Hsu, Ying-Han Roger, Kunanithy, Vitharani, Mackie, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
RNA: Processing and Catalysis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797255/
https://ncbi.nlm.nih.gov/pubmed/19778900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063263
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