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Phosphorylation of Protease-activated Receptor-2 Differentially Regulates Desensitization and Internalization
Protease-activated receptor 2 (PAR2) is a G protein-coupled receptor irreversibly activated by extracellular proteases. Activated PAR2 couples to multiple heterotrimeric G-protein subtypes including Gα(q), Gα(i), and Gα(12/13). Most activated G protein-coupled receptors are rapidly desensitized and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797212/ https://ncbi.nlm.nih.gov/pubmed/19815543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.048942 |
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