Csm3, Tof1, and Mrc1 Form a Heterotrimeric Mediator Complex That Associates with DNA Replication Forks

Mrc1 (mediator of replication checkpoint), Tof1 (topoisomerase I interacting factor), and Csm3 (chromosome segregation in meiosis) are checkpoint-mediator proteins that function during DNA replication and activate the effector kinase Rad53. We reported previously that Mrc1 and Tof1 are constituents...

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Detalhes bibliográficos
Main Authors: Bando, Masashige, Katou, Yuki, Komata, Makiko, Tanaka, Hirokazu, Itoh, Takehiko, Sutani, Takashi, Shirahige, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797203/
https://ncbi.nlm.nih.gov/pubmed/19819872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.065730
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