Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability.

Transforming growth factor-beta (TGF-beta) has been shown to stimulate synthesis of extracellular matrix proteins, both in animals and in cell culture. We found that mRNAs for alpha 1(I) collagen, fibronectin, and thrombospondin were markedly increased in TGF-beta-treated 3T3 (mouse) cells. For coll...

Descrición completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Penttinen, R P, Kobayashi, S, Bornstein, P
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1988
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3422482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.4.1105
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!