Cytoskeleton-dependent transport as a potential target for interfering with posttranscriptional HuR mRNA regulons

The ubiquitous mRNA binding protein human antigen R (HuR), a member of the embryonal lethal abnormal vision (ELAV) protein family has a critical impact on the posttranscriptional control of AU-rich element (ARE) bearing mRNA regulons implied in inflammation, senescence and carcinogenesis. HuR in add...

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Detalhes bibliográficos

Principais autores:	Wolfgang Eberhardt, Amel Badawi, Abhiruchi Biyanee, Josef Pfeilschifter
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2016-08-01
coleção:	Frontiers in Pharmacology
Assuntos:	RNA binding protein HuR mRNA stability mRNA trafficking cytoskeleton inhibitors
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00251/full
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