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Direct control of mitochondrial function by mTOR
mTOR is a central regulator of cellular growth and metabolism. Using metabolic profiling and numerous small-molecule probes, we investigated whether mTOR affects immediate control over cellular metabolism by posttranslational mechanisms. Inhibiting the FKBP12/rapamycin-sensitive subset of mTOR funct...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796909/ https://ncbi.nlm.nih.gov/pubmed/20080789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912074106 |
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