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Direct control of mitochondrial function by mTOR

mTOR is a central regulator of cellular growth and metabolism. Using metabolic profiling and numerous small-molecule probes, we investigated whether mTOR affects immediate control over cellular metabolism by posttranslational mechanisms. Inhibiting the FKBP12/rapamycin-sensitive subset of mTOR funct...

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Detalhes bibliográficos
Main Authors: Ramanathan, Arvind, Schreiber, Stuart L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796909/
https://ncbi.nlm.nih.gov/pubmed/20080789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912074106
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