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α-Synuclein contributes to GSK-3β-catalyzed Tau phosphorylation in Parkinson’s disease models
We have shown in the parkinsonism-inducing neurotoxin MPP(+)/MPTP model that α-Synuclein (α-Syn), a presynaptic protein causal in Parkinson’s disease (PD), contributes to hyperphosphorylation of Tau (p-Tau), a protein normally linked to tauopathies, such as Alzheimer’s disease (AD). Here, we investi...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Federation of American Societies for Experimental Biology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796901/ https://ncbi.nlm.nih.gov/pubmed/19369384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-120410 |
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